Saturday, April 20, 2013

Drug allergy and Food Allergy

Drug allergy unwanted side effect to certain medication.Food allergy same like Drug Allergy in effect,commonly skin reaction (rash).nousea ,vomiting, Diarrhea and swelling In mouth and throat. Drug allergy commonly occured secand time use of the medicine not first use.
Drug allergy is ife-threatening conditin but rare to couse Death.
Skin reactions of Drug allergy is measles-like rash so we must take good history for prober diagnosis and wright managment.
we should know that skin allergy may be occured after days or weeks from the first dose of the drug.(NB: good history)
Systemic symptomes and signs such as Rapid or irregular heart beat,Fainting.low Blood pressure and Chest tightness, wheezing, throat tightness
Now You can watch This Video and we hope that is informative:

Advice you to Read This topic if you are interested by Drug allergy and Food Allergy

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# Commenest drugs couse allergy such as codeine, morphine, nonsteroidal antiinflammatory drugs (NSAIDs, such as ibuprofen or indomethacin), and aspirin.
# Antibiotics such as penicillin, sulfa drugs, and tetracycline.
# Antiseizure medications such as phenytoin (Dilantin) or carbamazepine (Tegretol).
# Certain food allergies such as to eggs, soybeans, or shellfish
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Friday, April 19, 2013

Bronchial Asthma video from A-Z

Bronchial Asthma video from A-Z

Bronchial Asthma  common in USA about 20 million Americans have asthma.So we here will discus How we can deal with Allergy and what we should know about Bronchial Asthma by reading this topics and watching video from youtube also within days we will discus all allergy diseases in details so you can add your E-mail below to follow our blog.
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Bronchial Asthma Triggers:

Bronchial asthma triggers may include:
  • Smoking and passive smoking.
  • Infections such as colds, flu, or pneumonia.
  • Allergens such as food, pollen, mold, dust mites, and pet dander and others.
  • Excessive Exercise.
  • Air pollution and toxins,dust.
  • Weather, especially extreme changes in temperature.
  • Drugs (such as aspirin, NSAID, and beta-blockers).
  • Food additives (such as MSG).
  • Emotional stress and anxiety.
  • Perfumes and fragrances.
  • Acid reflux.
  • Rare: Singing, laughing, or crying.
--> Watch This Video:


Signs and Symptoms of Bronchial Asthma

One or more of the following signs and symptoms:
  • Shortness of breathing.
  • Tightness of chest.
  • Wheezing (patient can hear that in sever asthma)
  •  cough or a cough that keeps you awake at night.
Specially in:
*At  night or early morning
*Exercise – cold air
*Genetic Atopy ( IgE)
*Respiratory infections
*After asprin or B-blockers

Diagnosing Bronchial Asthma

Asthma tests may include:

  • Spirometry: A lung function test to measure breathing capacity and how well you breathe. You will breath into a device called a spirometer.
  • Peak Expiratory Flow (PEF): Using a device called a peak flow meter, you forcefully exhale into the tube to measure the force of air you can expend out of your lungs. Peak flow monitoring can allow you to monitor how well your asthma is doing at home.
  • Chest X-ray: Your doctor may do a chest X-ray to rule out any other diseases that may be causing similar symptoms as pneumonia.

Treating Bronchial Asthma

Aim of Treatment

*Relievers (Quick)
*Controllers (long term)
*Patient education

-Short-acting inhaled β2-agonists
Salbutamol,   Terbutaline
-Long-acting oral β2-agonists
Ipatropium, Tiotropium give synergestic bronchodilatation BUT of more benefit in COPD
Inhaled corticosteroids
=Budesonide/ beclomethasone/ fluticasoneuse any
=Start (400-1000 mcg/day approx. in 2 divided doses)
=Maintain for 3 months
=Taper slowly and keep at 200 mcg
=Safe for long-term use (years)
Famous available drugs :

lClenil modulite = Beclomethasone
Symbicort = Budesonide  + Formoterol
Pulmicort = budesonide
Seretide  = Fluticasone + Salmeterol
Flixotide = fluticasone
Foradil = formoterol
Atrovent = ipratropium bromide
Spiriva = tiotropium
Leukotrine receptor antagonist 
Benefit in exercise induced asthma – ch  rhinitis
Can be used alone - Not as effective as inhaled steroid
May be first-line for 2 to 5 yr. olds.
Montelukast (singulair)  - Zafirlukast
4 mg, 5 mg, 8 mg tabs available & sachets
Can be add on to ICS, IBD inhalers
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Step Up and Down  
1- Inhaled SABA  prn
2- Add inhaled steroid at 200-800 mcg/d (400 appropriate)
3- Add LABA : A- Good Control àcontinue    
                          B- Inadequate àincrease C/S 
                          C- No response à stop LABA increase C/S  & if still less controlled à+ trial leuktrienes or SR theophylline
4- Trial :  - C/S 2000 mcg/d   - Leuk     - SR theoph.  . Oral SABA 
5- Daily Steroid tab at lowest dose OR anti IgE . Continue maximum dose inhaled steroids .

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